Protection of cerulein-induced pancreatic fibrosis by pancreas-specific expression of Smad7
نویسندگان
چکیده
منابع مشابه
Protection of cerulein-induced pancreatic fibrosis by pancreas-specific expression of Smad7.
Pancreatic fibrosis is the hallmark of chronic pancreatitis, currently an incurable disease. Pancreatitis fibrosis is caused by deposition of extracellular matrix (ECM) and the underlying pathological mechanism remains unclear. In addition to its broad biological activities, TGF-beta is a potent pro-fibrotic factor and many in vitro studies using cell systems have implicated a functional role o...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2009
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2008.10.010